1 BOOK:
MacIntosh, B. R., Gardiner, P. F., & McComas, A. J. (2006). Skeletal muscle: Form and function (2nd ed.). Champaign, Ill.: Human Kinetics.
* You can find the book in the library here: ORIA
1 ELECTRONIC ARTICLE:
Review:
Sharples, A. P. (2017). Cellular and molecular exercise physiology: A historical perspective for the discovery of mechanisms contributing to skeletal muscle adaptation. Cellular and Molecular Exercise Physiology, 5(1), 1-13. https://doi.org/10.7457/cmep.v5i1.e10
* This article is available online: Click here to download.
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21 ELECTRONIC ARTICLES:
** NB! To open electronic articles off campus, you must use the following VPN connection: Click here to download.
WEEK 3-4:
TOPIC 1: Molecular Regulation of Skeletal Muscle Hypertrophy & Epigenetics
Delivered: Adam Sharples.
Overview - Book chapter:
Sharples, A. P., & Seaborne, R. A. (2019). Chapter ten: Exercise and DNA methylation in skeletal muscle. I D. Barh & I. I. Ahmetov (Eds.), Sports, exercise, and nutritional genomics: Current status and future directions (pp. 211-229). London: Academic Press.
* This PDF is available through Canvas.
(Cleared through BOLK 12.19./NIH bibl. - AGG)
Original Articles:
Sailani, M. R., Halling, J. F., Møller, H. D., Lee, H., Plomgaard, P., Pilegaard, H., . . . Regenberg, B. (2019). Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle. Scientific Reports, 9(1), 3272. https://doi.org/10.1038/s41598-018-37895-8 * This article is available online: Click here to download. Turner, D. C., Seaborne, R. A., & Sharples, A. P. (2019). Comparative transcriptome and methylome analysis in human skeletal muscle anabolism, hypertrophy and epigenetic memory. Scientific Reports, 9(1), 4251. https://doi.org./10.1038/s41598-019-40787-0. * This article is available online: Click here to download. TOPIC 2: Cellular models for studying skeletal muscle adaptation.Delivered: Piotr Gorski.
Overview Article:Kasper, A. M., Turner, D. C., Martin, N. R. W., & Sharples, A. P. (2018). Mimicking exercise in three-dimensional bioengineered skeletal muscle to investigate cellular and molecular mechanisms of physiological adaptation. Journal of Cellular Physiolohy, 233(3), 1985-1998. https://doi.org/10.1002/jcp.25840 * This article is available through Canvas.
(OK based on §15 of the Copyright Law) Orginal Articles:Aguilar-Agon, K. W., Capel, A. J., Martin, N. R. W., Player, D. J., & Lewis, M. P. (2019). Mechanical loading stimulates hypertrophy in tissue-engineered skeletal muscle: Molecular and phenotypic responses. Journal of Cellular Physiology, 234(12), 23547-23558. https://doi.org/10.1002/jcp.2892. * This article is available through Canvas.
(OK based on §15 of the Copyright Law) Khodabukus, A., Madden, L., Prabhu, N. K., Koves, T. R., Jackman, C. P., Muoio, D. M., & Bursac, N. (2019). Electrical stimulation increases hypertrophy and metabolic flux in tissue-engineered human skeletal muscle. Biomaterials, 198, 259-269. https://doi.org/10.1016/j.biomaterials.2018.08.058 * This article is available online: Click here to download. ____________________________________________________________________________________________________________________________________________
WEEK 4-6:TOPIC 3: Muscle mass and quality during aging and exerciseDelivered: Sive N. Aas.Overview Article: Tieland, M., Trouwborst, I., & Clark, B. C. (2018). Skeletal muscle performance and ageing. Journal of Cachexia, Sarcopenia and Muscle, 9(1), 3-19. https://doi.org/10.1002/jcsm.12238 * This article is available online: Click here to download.
Original Articles:Breen, L., Stokes, K. A., Churchward-Venne, T. A., Moore, D. R., Baker, S. K., Smith, K., . . . Phillips, S. M. (2013). Two weeks of reduced activity decreases leg lean mass and induces “Anabolic Resistance” of myofibrillar protein synthesis in healthy elderly. The Journal of Clinical Endocrinology & Metabolism, 98(6), 2604-2612. https://doi.org/10.1210/jc.2013-1502 * This article is available online: Click here to download.
Hvid, L. G., Strotmeyer, E. S., Skjødt, M., Magnussen, L. V., Andersen, M., & Caserotti, P. (2016). Voluntary muscle activation improves with power training and is associated with changes in gait speed in mobility-limited older adults: A randomized controlled trial. Experimental Gerontology, 80, 51-56. https://doi.org/10.1016/j.exger.2016.03.018 * This article is available online: Click here to download. St-Jean-Pelletier, F., Pion, C. H., Leduc-Gaudet, J.-P., Sgarioto, N., Zovilé, I., Barbat-Artigas, S., . . . Gouspillou, G. (2017). The impact of ageing, physical activity, and pre-frailty on skeletal muscle phenotype, mitochondrial content, and intramyocellular lipids in men. Journal of Cachexia, Sarcopenia and Muscle, 8(2), 213-228. https://doi.org/10.1002/jcsm.12139 * This article is available online: Click here to download.
TOPIC 4: Neuroendocrinology of fasting and exerciseDelivered: Jose CalbetOverview Article: Cahill, G. F. Jr. (2006). Fuel metabolism in starvation. Annual Review of Nutrition, 26(1), 1-22. https://doi.org/10.1146/annurev.nutr.26.061505.111258 * This article is available online: Click here to download. Original Articles:Calbet, J. A. L., Ponce-González, J. G., Calle-Herrero, J. d. L., Perez-Suarez, I., Martin-Rincon, M., Santana, A., . . . Holmberg, H.-C. (2017). Exercise preserves lean mass and performance during severe energy deficit: The role of exercise volume and dietary protein content. Frontiers in Physiology, 8(483). https://doi.org/10.3389/fphys.2017.00483 * This article is available online: Click here to download. Johannsen, D. L., Knuth, N. D., Huizenga, R., Rood, J. C., Ravussin, E., & Hall, K. D. (2012). Metabolic slowing with massive weight loss despite preservation of fat-free mass. The Journal of Clinical Endocrinology & Metabolism, 97(7), 2489-2496. https://doi.org/10.1210/jc.2012-1444 * This article is available online: Click here to download. Müller, M. J., Enderle, J., Pourhassan, M., Braun, W., Eggeling, B., Lagerpusch, M., . . . Bosy-Westphal, A. (2015). Metabolic adaptation to caloric restriction and subsequent refeeding: The Minnesota Starvation Experiment revisited. The American Journal of Clinical Nutrition, 102(4), 807-819. https://doi.org/10.3945/ajcn.115.109173 * This article is available through Canvas.
(OK based on §15 of the Copyright Law) ____________________________________________________________________________________________________________________________________________
WEEK 7-8:Topic 5: Protein and skeletal muscle growthDelivered: Truls RaastadOverview Article:Reidy, P. T., & Rasmussen, B. B. (2016). Role of ingested amino acids and protein in the promotion of resistance exercise-induced muscle protein anabolism. Journal of Nutrition, 146(2), 155-183. https://doi.org/10.3945/jn.114.203208 * This article is available online: Click here to download.
Original Articles:Atherton, P. J., Kumar, V., Selby, A. L., Rankin, D., Hildebrandt, W., Phillips, B. E., ... Smith, K. (2016). Enriching a protein drink with leucine augments muscle protein synthesis after resistance exercise in young and older men. Clinical Nutrition, 36(3), 888-895. https://doi.org/10.1016/j.clnu.2016.04.025. * This article is available through Canvas.
(OK based on §15 of the Copyright Law) Hamarsland, H., Handegard, V., Kåshagen, M., Benestad, H., & Raastad, T. (2019). No difference between spray dried milk and native whey supplementation with strength training. Medicine and Science in Sports Exercise, 51(1), 75-83. https://doi.org/10.1249/MSS.0000000000001758. * This article is available online: Click here to download. Macnaughton, L. S., Wardle, S. L., Witard, O. C., McGlory, C., Hamilton, D. L., Jeromson, S., ... Tipton, K. D. (2016). The response of muscle protein synthesis following whole-body resistance exercise is greater following 40 g than 20 g of ingested whey protein. Physiological Reports, 4(15), e12893. https://doi.org/10.14814/phy2.12893. * This article is available online: Click here to download.
TOPIC 6: Vitamin D in exercise and skeletal muscle adaptation
Delivered: Dr. Daniel OwensOverview Article:Owens, D. J., Allison, R., & Close, G. L. (2018). Vitamin D and the Athlete: Current perspectives and new challenges. Sports Medicine, 48(Suppl. 1), 3-16. https://doi.org/10.1007/s40279-017-0841-9 * This article is available online: Click here to download.
Original Articles:Agergaard, J., Trøstrup, J., Uth, J., Iversen, J. V., Boesen, A., Andersen, J. L., … Langberg, H. (2015). Does vitamin-D intake during resistance training improve the skeletal muscle hypertrophic and strength response in young and elderly men? A randomized controlled trial. Nutrition & Metabolism, 12, 32. https://doi.org/10.1186/s12986-015-0029-y * This article is available online: Click here to download. Ricca, C., Aillon, A., Bergandi, L., Alotto, D., Castagnoli, C., & Silvagno, F. (2018). Vitamin D receptor is necessary for mitochondrial function and cell health. International Journal of Molecular Sciences, 19(6), 1672. https://doi.org/10.3390/ijms19061672 * This article is available online: Click here to download.
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